14, 286289. Antinociceptive activity of the methanolic extract of Kaempferia Add organic fertilizers if you feel the need for them. (2010). -. Bioassay-guided Isolation of a Vasorelaxant Active Compound from Kaempferia Galanga L. Phytomedicine 13 (1-2), 6166. 10.1016/j.jksus.2017.05.009 Angew. Taken together, <i>K. galanga</i> L. is very potential to be developed as a prospective phytopharmaceutical for the treatment of oral mucosal ulceration in human after clinical trials. A., Ng, F. N., Ng, Y. C., and Hidayat, M. T. (2008). Unable to load your collection due to an error, Unable to load your delegates due to an error. The celebrated Houston heart physician, Dr. Michael DeBakey relied on galangal in the twilight of his life to help strengthen his heart. Anticholangiocarcinoma Activity and Toxicity of the Kaempferia Galanga Linn. 8600 Rockville Pike Immunopharmacol 14 (2), 209216. PDF ISSN 2320-3862 A comprehensive review of Kaempferia galanga L. Tropical The mechanism behind the anti-inflammatory action of K. galanga is associated with the presence of bioactive metabolites by inhibiting the release of inflammatory factors. What is Galangal? Your Guide to the Spice of Life Vhe on Twitter: "RT @AyaPamungkas: It's kencur, guys. Aromatic Structures of polysaccharides and other compounds isolated from K. galanga . Effects of Rhizoma Kaempferiae Volatile Oil on Tumor Growth and Cell Cycle of MKN-45 Human Gastric Cancer Cells Orthotopically Transplanted in Nude Mice. 2015 Jan 15;159:137-57. doi: 10.1016/j.jep.2014.10.040. Nazar, S., Ravikumar, S., and Prakash Williams, G. (2008). Research Strategy for Quality-Biomarkers of Traditional Chinese Medicine Based on Effect Benchmarks. It tastes sweet, spicy, and slightly bitter. Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells. Structures of diarylheptanoids, fatty acids and esters isolated from K. galanga . K. galanga is native to India, and commonly found in China, Myanmar, Indonesia, Malaysia, and Thailand (Wang and Tang, 1980; Santhoshkumari and Devi, 1991). The Plant List includes a further 3 scientific plant names of infraspecific rank for the genus Kaempferia.We do not intend The Plant List to be complete for names of infraspecific rank. Study on the Anti-carcinogenic Effects of Three Compounds in Kaempferia Galanga L. Wei Sheng Yan Jiu 31 (4), 247251. (2017a). At one point in history, a pound of this available commodity today could cost an entire sheep! We include products we think are useful for our readers. Sin. The anti-angiogenic effects of ethanol extract, trans-ethyl p-methoxycinnamate (34) and kaempferol (58) of K. galanga exhibited potent anti-angiogenic effect assessed by zebrafish angiogenic assay. Besides, 40 and 41 were first isolated and their structures were elucidated by the NMR, HR-MS and IR (Wu, 2016; Yao et al., 2018). Chin. The leaves of K. galanga have been reported to exert potent anti-inflammatory activity in a modified carrageenan-induced paw-edema test, supporting its traditional applications of ulcers and pains (Sulaiman et al., 2008). Res. Clipboard, Search History, and several other advanced features are temporarily unavailable. Cel Longev 2018, 9579262. doi:10.1155/2018/9579262, Yang, Y., Tian, S., Wang, F., Li, Z., and Li, Y. Specifically, compounds of galangol, galangin, gingerol, camphor, and eugenol have been the most well-studied for their positive affects. DC. Screening of the K. galanga focused nDEL against various protein targets will definitely help to illuminate the target network of K. galanga in the future. Sci. Rhizome against Ehrlich Ascites Carcinoma Cells. Med. doi:10.5958/0974-360X.2019.00365.2, Rahman, M. M., Amin, M. N., Ahamed, T., Ali, M. R., and Habib, A. J. Biol. Kaempferia galanga can be easily dug up during the winters and kept indoors in a pot with humid soil. No use, distribution or reproduction is permitted which does not comply with these terms. Repellent and Insecticidal Effects of the Essential Oil of Kaempferia Galanga Rhizomes to Liposcelis Bostrychophila (Psocoptera: Liposcelidae). If you buy through links on this page, we may earn a small commission Heres our process. National Library of Medicine Kaempferia spp. B., Wu, X. L., Zhang, L., and Wang, C. Y. (2011). Linear diarylheptanoids occurred frequently in plants of Zingiberaceae family, and all the diarylheptanoids isolated from K. galanga were linear. In the meantime, we recommend trying Hildegards galangal wine. Inhibitory Effect of Kaempferol on Inflammatory Response of Lipopolysaccharide-Stimulated Human Mast Cells. Our website services, content, and products are for informational purposes only. Both ginger and turmeric two close relatives of galangal root are also rich in polyphenols and have been linked to these benefits (7, 8, 9, 10, 11). THAI HERBS Krachai in Thai language refers to Kaempferia Galanga, so the real translation for this Thai root (Krachaidam) in English is Black Galanga and not Black Gingerwhich unfortunately most people like to refer to it as.It is recognised as one of the 5 economically important Thai Herbs in the country. Epub 2020 Mar 2. J. Appl. In fact, recent research on galanga has found significant antimicrobial and antioxidant properties contained in the galanga plant flowers. 18 (22), 79407947. Recently, the water-soluble polysaccharides (8088, Figure 7) from K. galanga. X-BY, UG, and BL supervised the findings of the work, and approved the manuscript for submission. (2015). The results showed that K. galanga had good antioxidant activity, among the five extracts, the activity of chloroform fraction was the best, and its SC50 on DPPH and ABTS were about 4 and 2 times that of the positive control (VC) respectively, followed by the ethyl acetate, n-butanol fraction, while petroleum ether fraction was poor and the water fraction was basically inactive (Xiang et al., 2018). It tolerates partial sun as long as the location is not too hot. This site needs JavaScript to work properly. There are numerous natural active compounds in galanga that demonstrate evidence or potential as medicinal substances. Bioorg. Rhizome on the Chemical-Induced Oral Mucosal Ulcer in Wistar Rats J Inflamm Res. In addition, fumigant toxicity (LC50 = 1.5mg/L air) of the essential oil against the booklouse also was observed (Liu et al., 2014). K. galanga is an aromatic medicinal herb. Comments have to be approved before they are shown here. 2022 Dec 7;9:1053811. doi: 10.3389/fnut.2022.1053811. Hepatoprotection by Kaempferia Galanga against Carbon Tetrachloride Induced Liver Damage in Rats. In addition, although K. galanga was widely used, there were few studies on its side effects. Galangal - Wikipedia RT @AyaPamungkas: It's kencur, guys. official website and that any information you provide is encrypted Turmeric has the most pungent and bitter flavor of the three. doi:10.1080/10496475.2020.1777614, Parjo, N. B., Mohamed Zulkifli, R., Md Salleh, M., and Tencomnao, T. (2018). It is a mild healing tonic that can be a great way to spice-up your day with the health benefits of galangal. Therefore, K. galanga is safe for the vital organs during treatment depending on the above toxicological studies. There, it is taken as part of the final three stages of initiation rituals along with species of Boletus mushrooms, Heimiella sp., Russula sp. The plant is a tropical one and will not tolerate any frost. The ethanolic extract of K. galanga and its major bioactive constituent trans-ethyl p-methoxycinnamate (34) could exert cytotoxic activity against cholangiocarcinoma cells (CL-6). exhibited ameliorating anticancer effects in DMH-induced rat colon carcinogenesis by regulating of various processes, such as proliferation, invasion, angiogenesis, apoptosis and inflammation (Gunasekaran et al., 2019). Ethnomedicinal uses, phytochemistry, pharmacological activities and toxicological profile of Glycosmis pentaphylla (Retz.) Golden milk also known as turmeric milk is a hot Indian drink made with milk and various spices. Calcium is incredibly essential for healthy bones and teeth. Extracts as UV Protecting and Antioxidant Agents in Sunscreen. K. galanga is an aromatic medicinal herb. 10 (6), 11491153. J. Chem. 113, 296302. Phytochemistry 34 (2), 415419. doi:10.1016/j.jpba.2015.03.020, Mohammad, S. P., Harindran, J., Kannaki, K. S., and Revathy, R. (2016). 2011) and is used as one of the traditional cuisine ingredients . 90 (2-3), 359365. doi:10.1603/EC13491. 30 (12), 25242529. Ali, H., Yesmin, R., Satter, M. A., Habib, R., and Yeasmin, T. (2018). Aroonrerk, N., and Kamkaen, N. (2009). Among them, 3-caren-5-one (1) was a monoterpene ketone, which was isolated from methanolic extract of K. galanga firstly (Kiuchi et al., 1987). Supercritical Carbon Dioxide Extraction of Ethyl P-Methoxycinnamate from Kaempferia Galanga L. Rhizome and its Apoptotic Induction in Human HepG2 Cells. Comparative Study of Kaempferol and Arbutin in Action of Melanocytes. Photos by Michelle Davis and Alani Davis. J. Nat. A total of 97 compounds have been obtained from the rhizome of K. galanga. A., Daud, I. Rhizome Ethanolic Extract. The galangal plant has a long history of medicinal and culinary uses. You can also use raw galangal root to make salves, tinctures, galangal tea, or Hildegards galangal wine. Chemical structures of main volatile components in K. galanga. Rhizome against Ehrlich Ascites Carcinoma Cells. Kaempferia galanga root. doi:10.1016/j.intimp.2012.07.007. doi:10.1016/j.toxrep.2019.05.014, Sulaiman, M. R., Zakaria, Z. Kaempferol (58) was investigated for the effect on tyrosinase activity, melanin content, and cell proliferation in human normal melanocytes. Not only do people around the world use it in their dishes, but it also has several medicinal properties that make it an essential ingredient in herb treatment. 107 (4), 17061712. 10.1186/s12906-017-1713-4 J Ethnopharmacol. Aromatic ginger, Kaempferia galanga. Structures of terpenoids isolated from K. galanga. In terms of quality control, the information about the cultivation environment, cultivars, processing, transportation, storage time, and quantitative studies of the index components are scarcely in the existing studies. It is worth noting that the dual quality control, chemical benchmark and effect benchmark has been generally accepted (Li et al., 2019; Zhu et al., 2019). J. Antimicrob. More recently, cyclic diarylheptanoids were isolated and elucidated. Theor. Serve before meals for optimal digestive benefits. Wang, Y., Jiang, Z.-T., Li, R., and Guan, W.-Q. Originated in Maritime Southeast Asia, this herb dates back to over two thousand years ago. Pharmacopoeia of the Peoples Republic of China. Moreover, the rhizomes of this plant are highly aromatic and have been used widely as spices, in food flavoring, pickles, cosmetics and in perfumery products. Spray with pesticides as required. Polyphenols are also thought to protect against mental decline, type 2 diabetes, and heart disease. Krachai Dam Is an herbaceous plant belonging to the Zingiberaceae. B., and Kong, L. Y. doi:10.1007/s10870-005-6145-1, Thiengsusuk, A., Chaijaroenkul, W., and Na-Bangchang, K. (2013). Kaempferia is a genus in the Zingiberaceae family found in southern & southeastern Asia. 30 (3), 386392. In Southern China, such as Guangxi, Guangdong, Yunnan are the main producing areas of K. galanga. Nevertheless, galangal root is the only one of the three that has been shown to potentially boost male fertility. Phytochemistry, Pharmacological Activities and Uses of Traditional Medicinal Plant Kaempferia Galanga L. - an Overview. Kaempferia galanga - an overview | ScienceDirect Topics Bookshelf Common medicinal uses of galanga include treatment of the following conditions: The essential oils of galanga are also packed with healing potential. (2018). Can Ginger and Turmeric Help Fight Pain and Sickness? Oil Bearing Plants 12 (4), 415421. Zhu, J. Y., Wang, Z. G., Zhang, H., Zhang, J. Q., Wu, F., and Shen, L. (2019). The acute and subacute toxicity tests of its rhizomes ethanol extract (maximum single oral dose up to 5,000mg/kg (b. w.), and daily dose of 1,000mg/kg (b. w.) for 30 consecutive days) showed that it has no significant toxicity regarding to the morbidity and mortality (Amuamuta et al., 2017). A bounty of natural medicine. Indian J. Physiol. In China, being a source of valuable bioactive compounds, it was used as a folk medicine due to its good curative effect on rheumatism, dry cough, colic, muscle pain, inflammations, as well as tumors (Park et al., 2005; Liu et al., 2010; He et al., 2012). This article reviews the benefits and safety of galangal root and compares it with ginger and turmeric. doi:10.1021/jf304169j, Hirschhorn, H. H. (1983). It is hardy to at least zone 8, surviving short duration freezes to 17 degrees Fahrenheit. Functionality-Independent DNA Encoding of Complex Natural Products. Int. Nat. Evaluation of Antiinflammatory and Analgesic Activities of Alcoholic Extract of Kaempferia Galanga in Rats. Serve warm or cold. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. (2018). Yao, F. Z. Galanga or galangal is a plant in the ginger family (Zingiber officinale). There are two types of galanga that are the most commonly used in cooking and as a healing plant: greater galangal (alpinia galanga) and lesser galangal (alpinia officinarum). They were isolated by steam distillation or supercritical fluid extraction, and analyzed by GC-MS. Also, adding fresh galangal root to your recipes may reduce your risk of vibriosis, an infection caused by eating undercooked shellfish (29, 30). The appealing aroma and health benefits of galanga are due to the same active ingredients. Bleeding time prolongation and the survival rate of mice was observed after 7days extract pre-treatment. Y-SW, X-DH, and F-FX provided critical revision of this article. (2019). Research on galangal esssential oil and extracts has been found a wide range of pharmacological and biological activities. Photos by Alani Davis. doi:10.1016/j.matpr.2019.06.100, Jagadish, P. C., Latha, K. P., Mudgal, J., and Nampurath, G. K. (2016). The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). In winters, this plant almost always goes dormant due to the low temperatures. doi:10.1055/s-2002-32900, Othman, R., Ibrahim, H., Mohd, M. A., Mustafa, M. R., and Awang, K. (2006). At Least 25% of the rhizome should be outside of the ground for proper growth. Ed. Akmal, N. S., Citra, K. D., and Nurpudji, A. T. (2017). Boreali-occident. Extraction, Characterization and Evaluation of Kaempferia Galanga L. (Zingiberaceae) Rhizome Extracts against Acute and Chronic Inflammation in Rats. Sharma A, Cooper R, Bhardwaj G, Cannoo DS. Ichwan, S. J. It's traditional spice & traditional medicine widely used across Indonesia and SEA regions. A., Hegazy, M.-E. F., Brajakishor Singh, C., et al. 2023 Feb 27;14:1099523. doi: 10.3389/fphar.2023.1099523. doi:10.1016/j.indcrop.2018.09.026. 5, 4365. Psyllium: Health Benefits of Soluble Fiber, Boesenbergia rotunda, also calledChinese gingerorfingerroot, Kaempferia galanga, also calledkencur,black galangalorsand ginger, Anti-hypertensive (lowers blood pressure), Nausea, motion sickness, and morning sickness, Respiratory ailments including: asthma, bronchitis, cough and sore throat, High Blood Sugar: to reduce blood sugar levels, Breath Freshener to treat chronic halitosis, Fertility treatment to increase sperm count and libido, Heart health including: lower blood pressure and improved circulation, Fresh galangal root, peeled and sliced or minced, Reduce heat and simmer for up to 30 minutes. doi: 10.4103/japtr.japtr_189_22. The database and code is licensed under a Galangal root is a spice closely related to ginger and turmeric and a popularly employed remedy in Ayurvedic and traditional Chinese medicine. Similarly, Kanjanapothi et al. 2020B1111110007); the National Natural Science Foundation of China (Nos. J. Pharm. Thus, there are many issues worthy of further study. Hildegard also recommended taking galangal with wine, which we refer to as galangal wine. In addition, it has been used widely as spices since its highly aromas. Isolation and Identification of Nematicide Component from Kaempferia Galanga L. Acta Bot. Furthermore, we will cover the the traditional uses of galanga, the health benefits of galanga, and how you can take galanga to improve your health. doi:10.3736/jcim20060413, Xie, J., Wang, S., Ma, P., Ma, F., Li, J., Wang, W., et al. Shintia, L. C., Wiranti, S. R., and Retno, W. (2018). (2004). Besides, the aqueous extract from its leaves have been reported to exert antinociceptive activity and anti-inflammatory activities in a dose dependently manner, supporting its traditional uses in the remedy of treat pain and mouth ulcer (Sulaiman et al., 2008). Int. : World Health Organization. We hope to provide valuable information for future in-depth investigations and applications of the herb. Chem. It is reported that both trans-and cis-ethyl p-methoxycinnamate (34, 39) could exert anti-carcinogeneic effect in an in vitro EBV assay with IC50 values of 5.5 and 9.5M (Xue and Chen, 2002). Would you like email updates of new search results? Leaves emerge heavily pigmented but these mature to predominately green with a series of brown/black eyelash marks. Does Too Much Turmeric Have Side Effects? (1994). doi:10.1081/FRI-200051897, Pedrete, T. A., Hauser-Davis, R. A., and Moreira, J. C. (2019). 2017 Jul 12;206:245-266. doi: 10.1016/j.jep.2017.05.007. In addition, biological evaluations should take appropriate effective dose, the frequency of administration and duration of treatment into consideration. (Kanjanapothi et al., 2004). In silicon docking indicated that 59 could interact with a series of key targets of SARS-CoV-2 (3CLpro, PLpro, Spro and RdRp) to exert potential anti-corona virus activity (Yu et al., 2020). Kaempferia Galanga has proved to be highly beneficial for our bodies. Anti-Inflammatory Activity and Wound Healing Effect of Kaempferia galangaL. Fresh galangal has a hint of fruity-spicy aroma, like a fir needle, while the dried version has a sweeter smell, much like cinnamon. Galangal powder is made from the dried roots, which are then ground into powder. See additional information. Although phytochemistry studies have isolated some compounds from the rhizomes of this plant, no study has documented the constituents separated from the leaves. All the data on K. galanga were based on different classical literary works, multiple electronic databases including SciFinder, Web of Science, PubMed, etc. The results showed 58 could strongly inhibit tyrosinase activity and melanin content of melanocyte without more toxicity or adverse side effect on proliferation of melanocytes, and suggested 58 was a promising tyrosinase inhibitor (Shang et al., 2011). K. galanga is from a dried rhizome of herb Kaempferia galanga L., belonging to the important family Zingiberaceae and genus Kaempferia. Chemical Composition and Larvicidal Activity of Edible Plant-Derived Essential Oils Against the Pyrethroid-Susceptible and -Resistant Strains of Aedes aegypti (Diptera: Culicidae). Biosynthetic Intermediate Probes for Visualizing and Identifying the Biosynthetic Enzymes of Plant Metabolites. doi:10.1128/JVI.78.20.11334-11339.2004, Yu, R., Chen, L., Lan, R., Shen, R., and Li, P. (2020). Biomed. (2018). Innovative breeding designs supported by information on the genomic resources and appropriate technologies could play a potential role to realize stable growth in K. galanga productivity and quality (Bohra et al., 2020). Epub 2021 Apr 29. Last update on 2022-07-20: Now containing 12727 plants. Keep it at 70-85 degrees Fahrenheit during the day and around 60-65 degree Fahrenheit during the night. Flowers either emerge in the spring just prior to the foliage or with the foliage continuing flowering through the summer. Meng X, Li J, Li M, Wang H, Ren B, Chen J, Li W. J Ethnopharmacol. B., Jeong, H. J., Kim, J. H., Kim, Y. M., Park, J. Y., Kim, D., et al. 15 (7), 10321036. Some are white flowered, some are lavender flowered, but this form seems to be more distinct than others though it freely hybridizes with other K. pulchra clones. Compound 26 was isolated from the chloroform fraction of 75% ethanol extract of K. galanga (Yao, 2018).
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