For diseases of the retina, including those related to diabetes: 50 milligrams three times daily. Another one of its exemplary effects is helping manage blood pressure levels. Proper nutrition is essential for ADHD treatment. Researchers suggest this benefit may be due to an increase in glutathione and SOD, two antioxidants that may reduce inflammation and oxidative stress in Crohns [76]. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. It also may increase the activity of genes that make collagen and hyaluronic acid in the body [64]. According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. DOI: Marini A, et al. Ask your doctor for advice. However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. Sign Up for the Latest Health News and Tips, Home Food and Nutrition Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. In the study, the placebo group had higher IgE antibodies to the birch allergen than those who took Pycnogenol during the allergy season [17]. Pycnogenol accelerates wound healing and reduces scar formation [Abstract]. 1. Regardless, a natural option is available and far worth the wait. The dosage in most clinical studies varied between 50-360 mg/day. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. Considering that about 1 of 3 adults in the U . According to researchers, it may help prevent the rise in free radicals typically seen after exercise, which could cause muscle fatigue and damage [9]. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. That way, your doctor can check on any potential side effects or interactions with medications. Tell your doctor about any supplements you're taking, even if they're natural. In a study of 76 people with allergic asthma, Pycnogenol (100 mg/day) added to conventional corticosteroid inhalers for 6 months helped 55% of them reduce inhaler use frequency and dosage. Next, the doctors discuss the link between salt and hypertension, and Dr. Steve gives his insight on drinking red wine for a healthy heart. Rating: 100%. 3. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. In clinical research, doses up to about 300 mg/day have been used for up to one year without major safety concerns [33, 37]. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. Make sure to seek out the advice of your physician prior to using pine bark extract or the branded name, Pycnogenol. Pine bark distill has been studied regarding its relationship to exercise performance, oxidative stress and excitement to torso that has been imposed by exercise. 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. In the control group, there were five thrombotic events; whereas the Pycnogenol-treated subjects only experienced nonthrombotic, local flare-ups. Various studies, referenced at uofmhealth.org, have shown that a daily dosage of Pycnogenol . Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. Side Effects of Pycnogenol. Luckily, the Native Americans told them about a tea prepared from the bark of a certain tree, which miraculously led to complete recovery. This condition is due to the pooling of blood in the veins of the lower legs. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. Beta 1-3D Glucan is recognized by cells in the immune system, and can modify your immune system responses. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. Typical doses range from 50 milligrams to 450 milligrams per day. Trees of this pine have been naturalized in Australia and New Zealand, where most Enzogenol is now made [7]. According to the National Institutes of Health, its safe for adults to take 50 to 450 milligrams of pine bark extract daily for up to one year. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . Any medication that you take, including herbal supplements, comes with certain risks. Blazs G, et al. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. PQQ (pyrroloquinoline quinone), also called methoxatin, is a vitamin-like compound that exists naturally in soil and a variety of foods, including spinach, kiwi, soybeans, and human breastmilk . Chewing gum with Pycnogenol (2.5 mg/piece) for 4 weeks reduced bad breath and mouth bacteria in a trial of 22 people [57]. Healthline Media does not provide medical advice, diagnosis, or treatment. Pycnogenol is similar to grape seed extract and cocoa polyphenols as those are the three most common . It also provides powerful antioxidant protection and helps inhibit inflammatory factors to support. They include: We need more research to know for sure if pycnogenol helps treat these conditions. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. The crew fell extremely ill from scurvy, an extreme lack of vitamin C. Cartiers crew crossed paths with a Quebec Indian who encouraged them to drink a tea made from pine bark and needles. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. For improving exercise capacity in athletes: 200 milligrams daily. While the aspirin reduced the risk for cardiovascular disease and colorectal cancer, among other cancers, the risk of gastrointestinal bleeding outweighed those benefits, creating more risks to the body. Eliminate blood clots. Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. Skin irritation. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. Pine bark extract has been studied regarding its relationship to exercise performance, oxidative stress and inflammation to body that has been imposed by exercise. Ginkgo biloba has been widely cultivated across the globe for a variety of uses, most of which are medicinal. In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. Lowers Blood Pressure. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. For mild high blood pressure: 200 milligrams daily. In one human study, some of the reported side effects of chanca piedra supplementation included: abdominal pain. A trial of 132 people found that Pycnogenol (150 mg/day) may improve risk factors of metabolic syndrome including lowering triglyceride levels, blood pressure, and fasting glucose, decreasing waist circumference, and increasing HDL cholesterol levels [29]. There's good evidence that pycnogenol helps with eye damage caused by diabetes. In this article, well summarize all the potential benefits and the scientific research surrounding pine bark extract and Pycnogenol. In the placebo group, the retinopathy worsened; whereas, in the Pycnogenol-treated group, there was no deterioration. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Pain score in the Pycnogenol-treated group was reduced by 56%, as compared to 9.6% reduction in the placebo group. Theres evidence that Pycnogenol may be a promising nootropic for various groups of people, including middle-aged professionals, students, and people with mild cognitive decline like brain fog. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). Pycnogenol treatment resulted in more normal-looking sperm. Pycnogenol has been well-tolerated in most studies performed thus far. Two doses of 100 mg of Pycnogenol were taken two to three hours before flights and two additional capsules taken six hours later then one capsule the next day. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Taking pine bark extract supports healthy blood pressure. If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. A clinically studied blend of Pycnogenol and a special bilberry extract (called Mirtogenol ) has been shown to provide benefits for vision and eye health. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. $47.99. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. There are several causes for erectile dysfunction, such as neurological and psychological issues. (2015). The usual recommended duration of treatment for topical application is 7 days for Pycnogenol cream and 6 weeks for Pycnogenol powder. Disease of the retina in the eye. After taking a break for one to two weeks, they can start taking it again for several weeks. These benefits appeared to persist for some time even after stopping supplementation [72]. (2006). In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. Twenty-one patients were given Pycnogenol at 150 mg daily and 18 patients received no treatment for a period of eight weeks. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Pycnogenol is officially extracted from the French maritime pine (Pinus pinaster), which grows in the southwest coast of France. It also lessened the amount of asthma medication they needed. Moreover, Pycnogenol lowered the chemical, leukotrienes responsible for asthma attacks. This ensures that there is a healthy flow of blood to and from the heart. Helps Increase Athletic Performance. Are there any risks to taking it? Learn more. As noted, aspirin can cause severe gastrointestinal issues. Start with a low dose so you can be sure it doesnt cause any side effects. Neuroprotective effect of Pycnogenol® following traumatic brain injury. Its quality is specified in the United States Pharmacopeia [3]. According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. Inhibits platelet aggregation like low-dose aspirin. During the first month on L-arginine, only five percent of patients experienced normal erection. Pycnogenol seems well-tolerated for use in adults for up to 6 months. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. Pycnogenol pine bark extracts contain a unique blend of flavonoids whose antioxidant action is over is 50 times more powerful than vitamin E, 20 times more powerful than vitamin C and 16 times more active than grapeseed extracts. For that reason, you should be careful taking pine bark if you have hypertension or diabetes. You can gradually increase how much you take once you get a better idea of how your body reacts to it. Here are the many health benefits believed to be possible with Pycnogenol: Reduces "leaky" blood vessels by making the wall proteins (collagen, elastin) more resistant to damage. DOI: Dvorkov M, et al. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. Boost gastrointestinal health. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. A clinical trial of 60 health professionals found that Pycnogenol (150 mg/day) may improve cognitive function, attention, mental performance and specific professional skills after 12 weeks. (2017). In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74].

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